Weiqiang Chen ,

Ph.D.

• Fellow, American Heart Association, 2023.
• The Micro and Nanoengineering Young Investigator Award, second place, 2021&2022.
• Chemical Communications Emerging Investigator Award, 2021.
• Healthy Longevity Award, New York Academy of Sciences and Japan Agency for Medical Research and Development, 2021.
• Biomedical Engineering Society Cellular and Molecular Bioengineering Rising Star Award, 2021.
• The Interstellar Initiative Early Career Investigators, New York Academy of Sciences and Japan Agency for Medical Research and Development, 2020.
• Best Paper Award, The 10^th Annual Meeting of Asian Cellular Therapy Organization, Sapporo, Japan, 2019.
• Chroma Young Investigator Award in Biomedical Engineering, 2019.
• Biomedical Engineering Society Cellular and Molecular Bioengineering Young Innovator Award, 2019.
• National Institute of General Medical Sciences Maximizing Investigators' Research Award (NIH Outstanding Investigator Award), 2019.
• Lab on a Chip Emerging Investigator, 2018.
• National Institute of Biomedical Imaging and Bioengineering Trailblazer Award, 2018.
• NYU Goddard Junior Faculty Fellowship, New York University, 2017. 
• NYU Whitehead Fellowship for Junior Faculty in Biomedical and Biological Sciences, New York University, 2017. 
• American Heart Association Scientist Development Award, American Heart Association, 2016. 
• ProQuest Distinguished Dissertation Award, University of Michigan, 2014. 
• Richard and Eleanor Towner Prize for Outstanding PhD Research, College of Engineering, University of Michigan, 2013.
• American Heart Association Predoctoral Fellowship, American Heart Association, 2013
• Baxter Young Investigator Award for distinguished research for critical care therapies and medical products, Baxter Healthcare Corporation, 2013
• Best Annual Speaker Award, Microfluidics in Biomedical Sciences Seminar Series of 2012-2013, University of Michigan, 2013.
• Outstanding Paper Award, 2nd ASME Global Congress on NanoEngineering for Medicine and Biology, Boston, MA, 2013.
• Best Poster Award, 7th Annual UM Engineering Graduate Symposium, University of Michigan, 2012.

Textbook

1. Raymond H.W. Lam and Weiqiang Chen, Biomedical Devices: Materials, Design, and Manufacturing, Springer Nature, 2019. ISBN 978-3-030-24236-7

Journal Articles

1. Ngoc Luu, Apratim Bajpai, Rui Li, Seojin Park, Mahad Noor, Xiao Ma, and Weiqiang Chen, Aging-associated Decline in Vascular Smooth Muscle Cell Mechanosensation is Mediated by Piezo1 Channel, Aging Cell, 2023, 00, e14036.
2. Ngoc Luu, Shuhao Zhang, Raymond H. W. Lam and Weiqiang Chen, Mechanical Constraints in Tumor Guide Emergent Spatial Patterns of Glioblastoma Cancer Stem Cells, Mechanobiology in Medicine, 2024, 2, 1, 100027.
3. Jiacheng He, Siqi Wu, Wu Chen, Albert Kim, Wen Yang, Chuanyu Wang, Zhengyang Gu, Jialiang Shen, Siyuan Dai, Weiqiang Chen, and Pengyu Chen, Calligraphy of Nanoplasmonic Bioink-Based Multiplex Immunosensor for Precision Immune Monitoring and Modulation, ACS Applied Materials & Interfaces, 2023, 15, 43, 50047-50057.
4. Mei ElGindi, Jiranuwat Sapudom, Anna Garcia Sabate, Brian Chesney Quartey, Aseel Alatoom, Mohammed Al-Sayegh, Rui Li, Weiqiang Chen, and Jeremy Teo, Effects of an aged tissue niche on the immune potency of dendritic cells using simulated microgravity, npj Aging, 2023, 9, 14.
5. Benteng Ma, Xinya Liu, Zhuoyu Zhang, Chao Ma, Rashik Chand, Saee Patwardhan, Chuanyu Wang, Soracha D. Thamphiwatana, Pengyu Chen, and Weiqiang Chen, A Digital Nanoplasmonic Microarray Immunosensor for Multiplexed Cytokine Monitoring during CAR T-Cell Therapy from a Leukemia Tumor Microenvironment Model, Biosensors and Bioelectronics, 2023, 115247.
6. Lang Zhou, Lunan Liu, Muammar Ali Chang, Chao Ma, Weiqiang Chen, Pengyu Chen, Spatiotemporal dissection of tumor microenvironment via in situ sensing and monitoring in tumor-on-a-chip, Biosensors and Bioelectronics, 2023, 225, 115064.
7. Alessandra Zanut, Rui Li, Ru Deng, Xiangyu Liu, Martin Rejhon, Weiqiang Chen, Marcus Weck, Giuseppe Maria de Peppo, Elisa Riedo, A Polymer Canvas with the Stiffness of the Bone Matrix to Study and Control Mesenchymal Stem Cell Response, Advanced Healthcare Materials, 2023, 2201503.
8. Lunan Liu, Chao Ma, Zhuoyu Zhang, Matthew T. Witkowski, Iannis Aifanti, Saba Ghassemi, Weiqiang Chen, Computational model of CAR T-cell immunotherapy dissects and predicts leukemia patient responses at remission, resistance, and relapse, Journal for ImmunoTherapy of Cancer, 2022, 10, e005360 .
9. Jiacheng He, Lang Zhou, Gangtong Huang, Jialiang Shen, Wu Chen, Chuanyu Wang, Albert Kim, Zhuoyu Zhang, Weiqiang Chen, Siyuan Dai, Feng Ding, Pengyu Chen, Enhanced Label-Free Nanoplasmonic Cytokine Detection in SARS-CoV-2 Induced Inflammation Using Rationally Designed Peptide Aptamer, ACS Applied Materials & Interfaces, 2022, 14, 43, 48464-48475. D
10. Jiyu Li, Dinglong Hu, Chee Kent Lim, Jifeng Ren, Xin Yao, Chao Ma, Marcos, Weiqiang Chen, Patrick K. H. Lee, and Raymond H. W. Lam, Selective Single-Bacteria Extraction Based on Capture and Release of Microemulsion Droplets, Scientific Reports, 2022, 15461.
11. Matthew T. Witkowski*, Soobeom Lee, Eric Wang, Anna Lee, Alexis Talbot, Chao Ma, Nikolaos Tsopoulidis, Justin Brumbaugh, Yaqi Zhao, Kathryn G. Roberts, Simon J. Hogg, Sofia Nomikou, Yohana Ghebrechristos, Palaniraja Thandapani, Charles Mullighan, Konrad Hochedlinger, Weiqiang Chen, Omar Abdel-Wahab, Justin Eyquem, Iannis Aifantis, NUDT21 limits CD19 levels through alternative mRNA polyadenylation in B cell acute lymphoblastic leukemia, Nature Immunology, 2022, 23, 1424-1432.
12. Zhuoyu Zhang, Lunan Liu, Chao Ma, Weiqiang Chen, A computational model of cytokine release syndrome during CAR T-Cell therapy, Advanced Therapeutics, 2022, 2200130.
13. Weiyi Qian, Tarik Hadi, Michele Silvestro, Xiao Ma, Cristobal F. Rivera, Apratim Bajpai, Rui Li, Zijing Zhang, Hengdong Qu, Rayan Sleiman Tellaoui, Annanina Corsica, Ariadne L. Zias, Karan Garg, Thomas Maldonado, Bhama Ramkhelawon, Weiqiang Chen, Microskeletal stiffness promotes aortic aneurysm by sustaining pathological vascular smooth muscle cell mechanosensation via Piezo1, Nature Communications, 2022, 13, 512.
14. Rui Li, Walida Ali, Chao Ma, Apratim Bajpai, Ngoc Luu, Aarushi Varshney, Camden Riley Rowe, Weiqian Chen*, Surface presentation of the noncanonical Wnt5a motif to cytotoxic CD8+ T-cells promotes their mechanotransduction and activation, Chemical Communications, 2021, 57, 12667-12670.
15. Chuanyu Wang, Chung-Hui Huang, Zhuangqiang Gao, Jialiang Shen, Jiacheng He, Alana MacLachlan, Chao Ma, Ya Chang, Wen Yang, Yuxin Cai, Yang Lou, Siyuan Dai, Weiqiang Chen, Feng Li, Pengyu Chen, Nanoplasmonic Sandwich Immunoassay for Tumor-Derived Exosome Detection and Exosomal PD-L1 Profiling, ACS Sensors, 2021, 6, 3308-3319.
16. Mei ElGindi, Jiranuwat Sapudom, Ibrahim Hamed Ibrahim, Mohamed Al-Sayegh, Weiqiang Chen, Anna Garcia-Sabaté, Jeremy Teo, May the Force Be with You (Or Not): The Immune System under Microgravity, Cells, 2021, 10, 8, 1941.
17. Zhuoyu Zhang, Lunan Liu, Chao Ma, Xin Cui, Raymond H. W. Lam, Weiqiang Chen, An in silico glioblastoma microenvironment model dissects the immunological mechanisms of resistance to PD-1 checkpoint blockade immunotherapy, Small Methods, 2021, 2100197.
18. Apratim Bajpai, Rui Li, Weiqian Chen, The Cellular Mechanobiology of Aging: From Biology to Mechanics, Annals of the New York Academy of Sciences, 2020, 1491, 3-24.Chao Ma, Yansong Peng, Hongtong Li, Weiqiang Chen, Organ-on-a-Chip 2.0: Fitting into the drug development pipeline, Trends in Pharmacological Sciences, 2020, 42, 2, 119-133.
19. Rui Li, Chao Ma, Haogang Cai, Weiqian Chen, The CAR T-cell Mechanoimmunology at a Glance, Advanced Science, 2020, 2002628.
20. Xin Cui, Jie Tong, Jimmy Yau, Apratim Bajpai, Jing Yang, Yansong Peng, Mrinalini Singh, Weiyi Qian, Xiao Ma, Weiqian Chen, Mechanical forces regulate vascular cell asymmetric alignment, Biophysical Journal, 2020, 119, 1771-1780.
21. Chao Ma, Matthew T. Witkowski, Jacob Harris, Igor Dolgalev, Sheetal Sreeram, Weiyi Qian, Jie Tong, Xin Chen, Iannis Aifantis, Weiqian Chen, Leukemia-on-a-Chip: Dissecting the chemo-resistance mechanisms in B-cell acute lymphoblastic leukemia bone marrow niche, Science Advances, 2020, 6, eaba5536.
22. Xin Cui, Chao Ma, Varshini Vasudevaraja, Jonathan Serrano, Jie Tong, Yansong Peng, Michael Delorenzo, Guomiao Shen, Joshua Frenster, Renee-Tyler Tan Morales, Weiyi Qian, Aristotelis Tsirigos, Andrew S. Chi, Rajan Jain, Sylvia C. Kurz, Erik P. Sulman, Dimitris Placantonakis, Matija Snuderl, Weiqiang Chen, Dissecting the heterogeneity of immunosuppressive tumor microenvironments in a Glioblastoma-on-a-Chip for optimized anti-PD-1 immunotherapy, eLife, 2020, 9, e52253.
23. Matthew T Witkowski, Igor Dolgalev, Nikki A Evensen, Chao Ma, Tiffany Chambers, Kathryn G Roberts, Sheetal Sreeram, Yuling Dai, Anastasia N Tikhonova, Audrey Lasry, Chunxu Qu, Deqing Pei, Cheng Cheng, Gabriel A Robbins, Joanna Pierro, Shanmugapriya Selvaraj, Valeria Mezzano, Marla Daves, Philip J Lupo, Michael E Scheurer, Cynthia A Loomis, Charles G Mullighan, Weiqiang Chen, Karen R Rabin, Aristotelis Tsirigos, William L Carroll, Iannis Aifantis, Extensive remodeling of the immune microenvironment in B cell acute lymphoblastic leukemia. Cancer Cell, 2020;37(6):867-882.e12.
24. Muhammedin Deliorman, Farhad K. Janahi, Pavithra Sukumar, Roaa Alnemari, Samar Fadl, Ayoub Glia, Weiqiang Chen, Mohammad A. Qasaimeh*, A microfluidic-atomic force microscopy platform for the capture and mechanical characterization of circulating tumor cells in prostate cancer, Microsystems & Nanoengineering, 2020, 6, 20.
25. Apratim Bajpai, Jie Tong, Weiyi Qian, Yansong Peng, Weiqiang Chen, The interplay between cell-cell and cell-matrix forces regulates cell migration dynamics, Biophysical Journal, 2019, 117, 1-10.
26. Pavithra Sukumar, Muhammedin Deliorman, Ayoola T. Brimmo, Roaa Alnemari, Deena Elsori, Weiqiang Chen, Mohammad A. Qasaimeh, Airplug-mediated isolation and centralization of single T cells in rectangular microwells for biosensing, Advanced Therapeutics, 2019, 1900085.
27. Qianbin Wang, Weiyi Qian, Xiaoyu Xu, Apratim Bajpai, Kevin Guan, Zijing Zhang, Roy Chen, Vittoria Flamini, and Weiqiang Chen, Energy-mediated machinery drives cellular mechanical allostasis, Advanced Materials, 2019, 1900453.
28. Weiyi Qian and Weiqiang Chen, Probing single-cell mechanical allostasis using ultrasound tweezers, Cellular and Molecular Bioengineering, 2019, s12195-019-00578-z.
29. Yuxin Cai, Jingyi Zhu, Jiacheng He, Yang Wen, Weiqiang Chen, and Pengyu Chen, Magnet Patterned Superparamagnetic Fe3O4/Au Core-Shell Nanoplasmonic Sensing Array for Label-Free High Throughput Cytokine Immunoassay, Advanced Healthcare Materials, 2019, 8, 1801478.
30. Weiqiang Chen, Steven G. Allen, Weiyi Qian, Zifeng Peng, Shuo Han, Xiang Li, Yubing Sun, Chelsea Fournier, Liwei Bao, Raymond H.W. Lam, Sofia D. Merajver, and Jianping Fu, Biophysical Phenotyping and Modulation of ALDH+ Inflammatory Breast Cancer Stem-like Cells, Small, 2019, 1802891.
31. Haoyu Wang, Renee-Tyler Tan Morales, Xin Cui, Jiongxian Huang, Weiyi Qian, Jie Tong, Weiqiang Chen, A Photoresponsive Hyaluronan Hydrogel Nanocomposite for Dynamic Immunomodulation, Advanced Healthcare Materials, 2018, 1801234.
32. Ini-Isabée Witzel, Rasha Nasser, Anna Sabate, Jiranuwat Sapudom, Chao Ma, Weiqiang Chen, Jeremy CM Teo, Deconstructing immune microenvironments of lymphoid tissues for reverse engineering, Advanced Healthcare Materials, 2018, 1801126.
33. Jingyi Zhu, Jiacheng He, Michael Verano, Ayoola T. Brimmo, Ayoub Glia, Mohammad A. Qasaimeh, Pengyu Chen, Jose O. Aleman, Weiqiang Chen,  An Integrated Adipose-Tissue-On-Chip Nanoplasmonic Biosensing Platform for Investigating Obesity-associated Inflammation, Lab on a Chip, 2018. 
34. Xin Cui, Renee-Tyler Tan Morales, Weiyi Qian, Haoyu Wang, Jean-Pierre Gagner, Igor Dolgalev, Dimitris Placantonakis, David Zagzag, Luisa Cimmino, Matija Snuderl, Raymond H. W. Lam*, Weiqiang Chen,  Hacking macrophage-associated immunosuppression for regulating glioblastoma angiogenesis, Biomaterials, 2018, 161, 164-178. 
35. Weiqiang Chen, Shuo Han, Weyi Qain, Shinuo Weng, Haiou Yang, Luis G. Villa-Diaz, Yubing Sun, Paul H. Krebsbach, Jianping Fu, Nanotopography regulates motor neuron differentiation of human pluripotent stem cells, Nanoscale, 2018, 10, 3556-3565. 
36. Xin Cui, Ya Liu, Dinglong Hu, Weiyi Qian, Dong Sun, Weiqiang Chen, Raymond H. W. Lam, A fluorescent microbead-based microfluidic immunoassay chip for immune cell cytokine secretion quantification, Lab on a Chip, 2018, 18, 522-531.
37. W. Qian, L. Gong, X. Cui, Z. Zhang, A. Bajpai, C. Liu, A. B. Castillo, J. C. M. Teo, W. Chen, Nanotopographic Regulation of Human Mesenchymal Stem Cell Osteogenesis, ACS Applied Materials & Interfaces, 2017, 9, 41794-41806.
38. S. Hill, W. Qian, W. Chen, J. Fu, Surface micromachining of polydimethylsiloxane for microfluidics applications, Biomicrofluidics, 2016, 10, 054114.
39. W. Chen, S. G. Allen, A. K. Reka, W. Qian, S. Han, J. Zhao, L. Bao, V. Keshamouni, S. D. Merajver, J. Fu, Nanoroughened adhesion-based capture of circulating tumor cells with heterogeneous molecular expression and metastatic characteristics, BMC Cancer, 2016, 16, 614.
40. C. Liu, X. Cui, T. M. Ackermann, V. Flamini, W. Chen, A. B Castillo, Osteoblast-Derived Paracrine Factors Regulate Angiogenesis in Response to Mechanical Stimulation, Integrative Biology, 2016, 8, 785-794.
41. S. Weng, Y. Shao, W. Chen, J. Fu, Mechanosensitive subcellular rheostasis drives emergent single-cell mechanical homeostasis, Nature Materials, 2016, 15, 961-967.
42. S. Hu, G. Liu, W. Chen, X. Li, W. Lu, R. H. W. Lam, J. Fu, Multiparametric biomechanical and biochemical phenotypic profiling of single cancer cells using elasticity microcytometer, Small, 2016, 12, 2300-2311.
43. Y. Zhang, A. Gorden, W. Qian, W. Chen, Engineering Nanoscale Stem Cell Niche: Direct Stem Cell Behavior at Cell–Matrix Interface, Advanced Healthcare Materials, 2015, 4, 1900-1914. 
44. W. Qian, Y. Zhang, W. Chen, Capturing Cancer: Emerging Microfluidic Technologies for the Capture and Characterization of Circulating Tumor Cells, Small, 2015, 11, 3850-3872.
45. W. Qian, Y. Zhang, W. Chen, Nanotopographic biomaterials for isolation of circulating tumor cells, Journal of Nanotechnology in Engineering and Medicine, 2014, 5, 040901.
46. W. Chen, Y. Shao, X. Li, and J. Fu, Nanotopograghical surfaces for stem cell fate control: Engineering mechanobiology from the bottom, Nano Today, 2014, 9, 759-784.
47. X. Li, W. Chen, G. Liu, W. Lu, and J. Fu, Continuous-flow microfluidic blood cell sorting for unprocessed whole blood using surface-micromachined microfiltration membranes, Lab on Chip, 2014, 14, 2565-2575.
48. X. Li, W. Chen, Z. Li, L. Li, H. Gu, and J. Fu, Emerging microengineering tools for functional analysis and phenotyping of blood cells, Trends in Biotechnology, 2014, 32, 586-594.
49. Y. Sun, K. M. Aw Yong, L. G. Villa-Diaz, X. Zhang, W. Chen, R. Philson, S. Weng, H. Xu, P. H. Krebsbach, and J. Fu, Hippo/YAP-mediated rigidity-dependent motor neuron differentiation of human pluripotent stem cells, Nature Materials, 2014, 13, 599-604.
50. B. Oh, N. Huang, W. Chen, J. Seo, P. Chen, T. T. Cornell, T. P. Shanley, J. Fu, and K. Kurabayashi, Integrated nanoplasmonic sensing in an optofluidic platform for human blood cellular functional immunoanalysis, ACS Nano, 2014, 8, 2667-2676.
51. Y. Shao, J. M. Mann, W. Chen, and J. Fu, Global Architecture of F-actin cytoskeleton regulates cell shape-dependent endothelial mechanotransduction, Integrative Biology, 2014, 6, 300-311.
52. W. Chen, N. Huang, B. Oh, R. H. W. Lam, R. Fan, T. T. Cornell, T. P. Shanley, K. Kurabayashi, and J. Fu, Surface-micromachined microfiltration membranes for efficient isolation and functional immunophenotyping of subpopulations of immune cells, Advanced Healthcare Materials, 2013, 2, 965-975.
53. Z. Fan, Y. Sun, D. Chen, D. Tay, W. Chen, C. X. Deng, and J. Fu, Acoustic tweezing cytometry for live-cell subcellular control of intracellular cytoskeleton contractility, Scientific Reports, 3, 2176.   
54. A. Singh, S. Suri, T. Lee, J. M.Chilton, M. T. Cooke, W. Chen, J. Fu, S. L. Stice, H. Lu, T. C. McDevitt, and A. J. García. Adhesive signature-based, label-free isolation of reprogrammed human induced pluripotent stem cells. Nature Methods, 2013, 10, 438-444. 
55. W. Chen, N. Huang, X. Li, Z. T. Yu, K. Kurabayashi and J. Fu. Emerging microfluidic tools for functional immunophenotyping: A new potential paradigm for immune status characterization. Frontiers in Oncology, 2013, 3, 98.
56. W. Chen, S. Weng, F. Zhang, S. Allen, X. Li, L. Bao, R. H. W. Lam, J. A. Macoska, S. D. Merajver, and J. Fu, Nanoroughened surfaces for efficient capture of circulating tumor cells without using capture antibodies, ACS Nano, 2013, 7, 566-575. 
57. W. Chen, Y. Sun and J. Fu, Microfabricated nanotopological surfaces for study of adhesion-dependent cell mechanosensitivity, Small, 2013, 9, 81-89.
58. W. Chen, R. H. W. Lam and J. Fu, Photolithographic surface micromachining of polydimethylsiloxane (PDMS), Lab on a Chip, 2012, 12, 391-395. 
59. N. Huang, W. Chen, B. Oh, T. Cornell, T. Shanley, J. Fu and K. Kurabayashi,  An integrated microfluidic platform for in-situ cellular cytokine secretion immunophenotyping, Lab on a Chip, 2012, 12, 4093-4101. 
60. W. Chen, L. G. Villa-Diaz, Y. Sun, S. Weng, R. H. W. Lam, L. Han, R. Fan, P. H. Krebsbach, and J. Fu, Nanotopography influences adhesion, spreading, and self-renewal of human embryonic stem cells, ACS Nano, 2012, 6, 4094-4103.
61. Y. Sun, L. G. Villa-Diaz, R. H. W. Lam, W. Chen, P. H. Krebsbach and J. Fu, Matrix mechanics regulates fate decisions of human embryonic stem cells, PLoS ONE, 2012, 7, e37178.
62. R. H. W. Lam, Y. Sun, W. Chen and J. Fu, Elastomeric microposts integrated into microfluidics for flow-mediated endothelial mechanotransduction analysis, Lab on a Chip, 2012, 12, 1865-1873.
63. Y. Wu, Y. Lu, W. Chen, J. Fu and R. Fan, In silico experimentation of glioma microenvironment development and anti-tumor therapy, PLoS Computational Biology, 2012, 8, e1002355.
64. W. Chen, K. P. Chen, M. D. Thoreson, A. V. Kildishev and V. M. Shalaev, Ultrathin, ultrasmooth and low-loss silver films via wetting and annealing, Applied Physics Letter, 2010, 97, 21107. 
65. W. Chen, M. D. Thoreson, A. V. Kildishev and V. M. Shalaev, Fabrication and Optical Characterizations of Smooth Silver-Silica Nanocomposite Films, Laser Physics Letters, 2010, 7, 677-684.
66. W. Chen, M. D. Thoreson, S. Ishii, A. V. Kildishev and V. M. Shalaev, Ultra-thin ultra-smooth and low-loss silver films on a germanium wetting layer, Optics Express, 2010, 18, 5124-5134.
67. Z. Su, G. Ding, W. Lu, W. Chen, Broadband circularly polarized CPW-fed slot antenna array for millimeter wave application, Microelectronics Journal, 2009, 40, 1192-1195.
68. R. B. Nielsen, M. D. Thoreson, W. Chen, A. Kristensen, J. M. Hvam, V. M. Shalaev and A. Boltasseva, Toward superlensing with metal–dielectric composites and multilayers, Applied Physics B, 2010, 100, 93-100.
69. W. Chen, G. Ding, B. Li, X. Sun, Design and simulation of MEMS-based broadband unidirectional CPW-fed rectangular slot antenna, Microsystem Technologies, 2008, 14, 343-347.
70. W. Chen, G. Ding, Z. Su and B. Li, A novel MEMS-based CPW-fed slot antenna for broadband circular polarization and unidirectional radiation, Journal of Micromechanics and Microengineering, 2007, 17, 2352–2359.
71. Z. Yang, G. Ding, W. Chen, S. Fu, X. Sun and X. Zhao, Design, simulation and characterization of inertia micro-switch fabricated by non-silicon surface micromachining, Journal of Micromechanics and Microengineering, 2007, 17, 1598–1604. 

NYU Clinical and Translational Science Institute Pilot Project

Project Title: “Lymph node-on a Chip: Modeling Human Adaptive Immune Responses to Assess Vaccine Efficacy”

Granting Agency: New York University                         

Principal Investigator: Weiqiang Chen

Award Period: 01/01/2024-12/31/2025  

AHA Institutional Award for Undergraduate Student Training                    

Project Title: “NYU Cardiovascular Engineering Summer Undergraduate Research Program”

Granting Agency: American Heart Association                          

Principal Investigator: Weiqiang Chen                          

Award Period: 01/01/2024-12/31/2026  

Arthritis Foundation Rheumatoid Arthritis Research Program         

Project Title: “Examination of Pathotype-specific Biology and Treatment Response using Microbioengineered and RA Patient-Derived Synovium-on-a-Chip”

Granting Agency: Arthritis Foundation                          

Principal Investigator: Theresa Wampler Muskardin (HSS) & Weiqiang Chen               

Award Period: 01/01/2024-12/31/2026  

NSF Engineering of Biomedical Systems Grant (CBET-2103219)         

Project Title: “Bioengineering Leukemic Bone Marrow Niche for Dissecting the Heterogeneous Leukemia Chemo-resistance Mechanisms”

Granting Agency: National Science Foundation                       

Principal Investigator: Weiqiang Chen

Award Period: 07/01/2021–08/30/2024  

NSF Innovation Corps (I-Corps) program (CBET-2221959)                         

Project Title: “I-Corps: Bioengineered CAR-T Chips for Screening Better CAR T-Cell Immunotherapy”

Granting Agency: National Science Foundation                        

Principal Investigator: Weiqiang Chen              

Award Period: 05/01/2022–10/31/2023

New York University Mega-grant Initiative Fund                                          

Project Title: “Development of a Patient-derived Pancreatic Cancer on Chip Model for Assessing Novel Immunotherapy”

Granting Agency: New York University Provost Office              

Principal Investigator: Weiqiang Chen              

Award Period: 06/15/2022–06/30/2023

Arthritis National Research Foundation Grant                                        

Project Title: “Type I Interferon Pathway Activity Informs TNF-inhibitor Treatment Response in Rheumatoid Arthritis”

Granting Agency: Arthritis National Research Foundation                                            

Principal Investigator: Theresa Wampler Muskardin (HSS) & Weiqiang Chen

Award Period: 06/01/2022–05/31/2023

The Colton Center for Autoimmunity Innovative Grant

Project Title: “Impact of type I interferons on Rheumatoid arthritis patient monocytes, monocyte-derived macrophages and fibroblast-like synoviocytes using a novel vascularized pannus-on-a-chip model”

Granting Agency: The Colton Center for Autoimmunity 

Principal Investigator: Weiqiang Chen & Theresa Wampler Muskardin

Award Period: 07/01/2021–06/30/2022

NIGMS Administrative Supplements for Equipment (3R35GM133646-02S1)

Project Title: “Purchase of Spinning Disk Confocal Microscope”

Granting Agency: National Institute of General Medical Sciences 

Principal Investigator: Weiqiang Chen

Award Period: 07/01/2020-06/30/2021

Innovative Research in Cancer Nanotechnology (1R01CA243001-01)

Project Title: “Map Leukemia-immune Cell Communication with Nanoplasmon Ruler in CAR T-Cell Immunotherapy”

Granting Agency: National Cancer Institute                   

Principal Investigator: Weiqiang Chen & Pengyu Chen (Auburn University)

Award Period: 07/01/2020-06/30/2025 

NIGMS Maximizing Investigators' Research Award for Early Stage Investigators (1R35GM133646-01) Project Title: “Dissecting and Engineering CAR T-cell Function for Optimized Immunotherapy”

Granting Agency: National Institute of General Medical Sciences  

Principal Investigator: Weiqiang Chen

Award Period: 09/01/2019-06/30/2024

NIBIB Trailblazer Award (1R21EB025406)                                        

Project Title: “Engineered Glioblastoma Tumor Immunity for Personalized Immunotherapy”

Granting Agency: National Institute of Biomedical Imaging and Bioengineering                            

Principal Investigator: Weiqiang Chen & Matija Snuderl (NYU Department of Pathology)    

Award Period: 09/01/2018–05/31/2022       

NSF Nano-biosensing Grant (CBET-1701322)                      

Project Title: “Collaborative Research: Plasmofluidic Nanoantenna-Superlens Biosensor for Single-Cell Functional Immunophenotyping”

Granting Agency: National Science Foundation                       

Principal Investigator: Weiqiang Chen & Pengyu Chen (Auburn University)                    

Award Period: 09/01/2017–08/31/2020

AHA Scientist Development Grant (16SDG31020038)                 

Project Title: “Nanotopography-Dependent Neural Stem Cell Induction of Human Induced Pluripotent Stem Cells for Post Stroke Neural Rehabilitation”

Granting Agency: American Heart Association                         

Principal Investigator: Weiqiang Chen              

Award Period: 07/01/2016–06/30/2019

NYUAD Research Enhancement Fund                                                        

Project Title: “Single Cell Capture and Nanomechanical Phenotyping of Prostate Circulating Tumor Cells using a Novel Microfluidic Platform”

Granting Agency: New York University Abu Dhabi                                   

Principal Investigator: Mohammad Qasaimeh (NYU Abu Dhabi) & Weiqiang Chen

Award Period: 09/01/2017–08/31/2019     

New York University Mega-grant Initiative Grant                                      

Project Title: “Bioengineer in vitro Glioma Vascular Microenvironment Model”

Granting Agency: New York University Provost Office             

Principal Investigator: Weiqiang Chen              

Award Period: 04/01/2017–03/31/2018

New York University Whitehead Fellowship for Junior Faculty in Biomedical and Biological Sciences    

Project Title: “Glioma-on-a-Chip for in vitro Validation of Personalized PD-1/PD-L1 Immunotherapy”

Granting Agency: New York University                        

Principal Investigator: Weiqiang Chen              

Award Period: 09/01/2017–08/31/2018

New York University CTSI Pilot Project                                            

Project Title: “Microfluidic Functional Immunophenotyping of Human Adipose Tissue Immune Cells”

Granting Agency: New York University                        

Principal Investigator: José O. Alemán (NYU Department of Medicine) & Weiqiang Chen

Award Period: 04/01/2017–03/31/2018      

New York University Global Seed Grants for Collaborative Research          

Project Title: “Plasmonic-based Microfluidic Biosensor for Immune Cell Phenotyping”

Granting Agency: New York University                        

Principal Investigator: Weiqiang Chen & Mohammad Qasaimeh (NYU Abu Dhabi)

Award Period: 04/01/2016–03/31/2018

New York University Research Challenge Fund                                     

Project Title: “Nanotopography Mediated Neural Differentiation of Human Induced Pluripotent Stem Cells for the Post Stroke Rehabilitation of Neurological Impairments”

Granting Agency: New York University                        

Principal Investigator: Weiqiang Chen

Award Period: 06/01/2015–05/31/2016